The laminar flow dehydrogenating\u00a0tunnels are the result of years of research\u00a0and experience in\u00a0the field\u00a0of serialization\u00a0and degeneration.The\u00a0tunnels\u00a0are\u00a0suitable\u00a0for\u00a0being\u00a0included\u00a0in continuous\u00a0production\u00a0lines, which require a sterilization and degeneration\u00a0process by\u00a0dry heat for glass containers such as vials, ampoule, etc.<\/p>\n
The heating of containers is made by using hot air, treated with\u00a0pre-flters and absolute filters\u00a0HEPA or ULPA, which protect\u00a0the container during the complete preheating sterilizing\u00a0dehydrogenating\u00a0and cooling process; along the entire length of\u00a0the tunnel the air quality is lO5 as per lSO 14644.<\/p>\n
The machine\u00a0designed and built according to cGMP standards, uses solution\u00a0sat the forefront of technology and therefore is able to guarantee\u00a0the repeatability and the absolute control of the process, and\u00a0the easy use.<\/p>\n
This series of Pharma Glass Vials Depyrogeneration models meet the requirements of yy 0217.3-2005 pharmaceutical industry standard, and meet the GMP specifications. The heat distribution in the tunnel is uniform, and the temperature difference in the sterilization section is \u00b1 5 \u2103. In the hot air circulation sterilization tunnel oven, high efficiency filters are installed in the bottle inlet section, heating and sterilization section and cooling section, so that the medicine bottle is sent out of the oven through stainless steel mesh belt from the bottle inlet section through the heating and sterilization section to the cooling section. During the process, the bottle mouth is always under 100 level protection to ensure that the medicine bottle is not polluted.<\/p>\n
A pharmaceutical depyrogenation heating tunnel is a continuous dry-heat processing system designed to sterilize and reduce endotoxin levels on glass containers, such as pharmaceutical vials and ampoules. It typically includes preheating, high-temperature treatment and cooling zones, allowing washed containers to move directly toward an aseptic filling line.<\/p>\n
Sterilization is intended to eliminate viable microorganisms, while depyrogenation aims to inactivate or remove pyrogens, particularly bacterial endotoxins. A properly validated dry-heat process for glass containers may achieve both objectives. The required performance must be established through appropriate process validation.<\/p>\n
A commonly applied acceptance target is at least a 3-log10 reduction in endotoxin concentration, equivalent to 99.9% reduction. Validation should use representative containers challenged with endotoxin and include suitable recovery controls, quantitative testing and justified worst-case processing conditions.<\/p>\n
The required temperature depends on the vial material, container mass, conveyor speed, heating profile and validated process. The supplier should propose a suitable temperature range and demonstrate performance through heat-distribution, heat-penetration and endotoxin-challenge studies. A single temperature setting cannot establish process effectiveness.<\/p>\n
Residence time depends on the effective heating-zone length and conveyor belt speed. However, geometric residence time is not the same as the time the vial itself spends at the target temperature. Heat-penetration studies are required to establish the actual vial temperature profile and effective thermal exposure.<\/p>\n
-The complete procedure of the equipment: bottle feeding -> preheating -> sterilizing -> cooling and automatic rolling out the bottles. -PLC control, touch screen interface, easy to operate. -The control system uses SCR module being coordinated with that of temperature controller PID auto tuning and allows of current output curves appearing linear status to make the chamber temperature heat distribution more uniform. Under a normal regulation, the heat distribution is in the acceptance range of within \u00b1 5\u2103 at a test of running free.<\/p>\n
Functional specification (FS) Design specification (DS) Installation Qualification (IQ) Operational Qualification (OQ) Operation manual Maintenance manual Material certification Control loop drawing Instrument list Electrical schematic P & ID drawing Machine structure drawing<\/p>\n
01 DESCRIPTION Working Principle:<\/p>\n
Working Principle:<\/p>\n
02 SPECIFICATION<\/p>\n
03 FAQ<\/p>\n
04 FEATURE<\/p>\n
05 DOCUMENTATION<\/p>","protected":false},"excerpt":{"rendered":"
DESCRIPTION The laminar flow dehydrogenating\u00a0tunnels are the result of years of research\u00a0and experience in\u00a0the field\u00a0of serialization\u00a0and degeneration.The\u00a0tunnels\u00a0are\u00a0suitable\u00a0for\u00a0being\u00a0included\u00a0in continuous\u00a0production\u00a0lines, which require […]<\/p>\n","protected":false},"featured_media":5659,"menu_order":0,"template":"","cxb_product_category":[19],"cxb_product_tag":[63,73,74],"class_list":["post-5690","cxb_products","type-cxb_products","status-publish","has-post-thumbnail","hentry","cxb_product_category-pharma-sterilezation-and-drying-machine","cxb_product_tag-depyrogenation","cxb_product_tag-glass-vials-sterilization","cxb_product_tag-heating-tunnel"],"_links":{"self":[{"href":"https:\/\/28.feihuaweiye.com\/ar\/wp-json\/wp\/v2\/cxb_products\/5690","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/28.feihuaweiye.com\/ar\/wp-json\/wp\/v2\/cxb_products"}],"about":[{"href":"https:\/\/28.feihuaweiye.com\/ar\/wp-json\/wp\/v2\/types\/cxb_products"}],"version-history":[{"count":3,"href":"https:\/\/28.feihuaweiye.com\/ar\/wp-json\/wp\/v2\/cxb_products\/5690\/revisions"}],"predecessor-version":[{"id":6342,"href":"https:\/\/28.feihuaweiye.com\/ar\/wp-json\/wp\/v2\/cxb_products\/5690\/revisions\/6342"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/28.feihuaweiye.com\/ar\/wp-json\/wp\/v2\/media\/5659"}],"wp:attachment":[{"href":"https:\/\/28.feihuaweiye.com\/ar\/wp-json\/wp\/v2\/media?parent=5690"}],"wp:term":[{"taxonomy":"cxb_product_category","embeddable":true,"href":"https:\/\/28.feihuaweiye.com\/ar\/wp-json\/wp\/v2\/cxb_product_category?post=5690"},{"taxonomy":"cxb_product_tag","embeddable":true,"href":"https:\/\/28.feihuaweiye.com\/ar\/wp-json\/wp\/v2\/cxb_product_tag?post=5690"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}