{"id":5647,"date":"2026-10-23T13:25:44","date_gmt":"2026-10-23T13:25:44","guid":{"rendered":"https:\/\/28.feihuaweiye.com\/sterilization-heating-tunnel\/"},"modified":"2026-11-07T05:49:24","modified_gmt":"2026-11-07T05:49:24","slug":"sterilization-heating-tunnel","status":"publish","type":"page","link":"https:\/\/28.feihuaweiye.com\/id\/sterilization-heating-tunnel\/","title":{"rendered":"Sterilization Heating Tunnel"},"content":{"rendered":"\t\t
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DEPYROGENATING TUNNEL<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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HOW DEPYROGENATING TUNNEL WORK<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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The laminar flow dehydrogenating tunnels are the result of years of research and experience in the field of serialization and degeneration.The tunnels are suitable for being included in continuous production lines, which require a sterilization and degeneration process by dry heat for glass containers such as vials, ampoule, etc.\n\nThe heating of containers is made by using hot air, treated with pre-flters and absolute filters HEPA or ULPA, which protect the container during the complete preheating sterilizing dehydrogenating and cooling process; along the entire length of the tunnel the air quality is lO5 as per lSO 14644. \n\nThe machine designed and built according to cGMP standards, uses solution sat the forefront of technology and therefore is able to guarantee the repeatability and the absolute control of the process, and the easy use.<\/p>\n\t\t\t\t\t<\/div>\n \t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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DEYROGENATION HEATING TUNNEL<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Continuous Dry-Heat Sterilization and Depyrogenation Tunnel for Vial Sterilization and Depyrogenation: Suitable for high-volume vial production. Cleaned vials enter the tunnel and undergo preheating, dry heat treatment, and cooling before being conveyed to the filling station. Features include high-temperature treatment and proven heat treatment effectiveness, filtered air protection, contamination control in the cooling section, and stable upstream and downstream connections. It is designed for direct connection to bottle washing machines and aseptic filling machines.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tSend Inquiry<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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HEATING DYRING STERILIZATION TUNNEL<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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As materials move along a specialized conveyor belt through a high-frequency electromagnetic field that rapidly and continuously fluctuates, the polar orientation of the molecules within the materials shifts in response to the changing external electric field. This induces molecular motion and internal friction. The electromagnetic energy is converted into thermal energy, raising the temperature of the materials and enabling rapid, low-temperature drying. Regarding sterilization: Microwave sterilization eliminates microorganisms through the combined action of thermal and non-thermal effects. Application for 2ml \u2013 15ml glass vials.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tSend Inquiry<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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FAQ OF VIALS STERILIZATION TUNNEL<\/h2>\t\t\t\t<\/div>\n\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tWhat is a pharmaceutical depyrogenation heating tunnel?<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
\n A pharmaceutical depyrogenation heating tunnel is a continuous dry-heat processing system designed to sterilize and reduce endotoxin levels on glass containers, such as pharmaceutical vials and ampoules. It typically includes preheating, high-temperature treatment and cooling zones, allowing washed containers to move directly toward an aseptic filling line. <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tDifference between sterilization and depyrogenation?<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
\n Sterilization is intended to eliminate viable microorganisms, while depyrogenation aims to inactivate or remove pyrogens, particularly bacterial endotoxins. A properly validated dry-heat process for glass containers may achieve both objectives. The required performance must be established through appropriate validation <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tWhat endotoxin reduction should a depyrogenation tunnel achieve?<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
\n A commonly applied acceptance target is at least a 3-log10 reduction in endotoxin concentration, equivalent to 99.9% reduction. Validation should use representative containers challenged with endotoxin and include suitable recovery controls, quantitative testing and justified worst-case process conditions. <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tWhat operating temperature is required for a vial tunnel?<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
\n The required temperature depends on the vial material, container mass, conveyor speed, heating profile and validated process. The supplier should propose a suitable temperature range and demonstrate performance through heat-distribution, heat-penetration and endotoxin-challenge studies. A single temperature setting cannot establish process effectiveness. <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tHow is the residence time in the heating zone determined?<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
\n Residence time depends on the effective heating-zone length and conveyor belt speed. However, geometric residence time is not the same as the time the vial itself spends at the target temperature. Heat-penetration studies are required to establish the actual vial temperature profile and effective thermal exposure <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\tDoes a depyrogenation tunnel should require HEPA filtration?<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t
\n Yes. For pharmaceutical tunnel applications covered by EU GMP Annex 1, all air supplied to the tunnel must pass through at least HEPA filtration, with periodic filter-integrity testing at least every six months. Airflow direction and pressure-differential profiles should also be assessed to protect the Grade A sterilizing zone. <\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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DEYPROGENATION HEATING TUNNEL BUYING GUIDE<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Selecting the right pharmaceutical depyrogenation tunnel is an important decision for manufacturers of sterile injectable drugs, vaccines, and other parenteral products. The tunnel must provide reliable dry-heat treatment, consistent endotoxin reduction, controlled airflow, and protected transfer of sterilized glass containers to the aseptic filling area.<\/p>

For pharmaceutical companies in the United States and Europe, purchasing decisions should consider more than heating temperature and production speed. Equipment design, thermal performance, HEPA filtration, line integration, data recording, and process validation are all essential.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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Model<\/th>RHT-S50\/2200<\/th>RHTS-620\/3400<\/th>RHTS-620\/4250<\/th>RHTS-620\/5000<\/th>\n<\/tr>\n<\/thead>\n
Application<\/td>2-10ml<\/td>2-10ml<\/td>2-15ml<\/td>2-20ml<\/td>\n<\/tr>\n
Sterilization<\/td>100-200<\/td>300-150<\/td>400-100<\/td>600-80<\/td>\n<\/tr>\n
Power w380v,50HZ<\/td>25KW<\/td>45kw<\/td>74kw<\/td>80kw<\/td>\n<\/tr>\n
Working Temperature<\/td>250\u2103-350\u2103<\/td>250\u2103-350\u2103<\/td>250\u2103-350\u2103<\/td>250\u2103-350\u2103<\/td>\n<\/tr>\n
Un-Loading<\/td>\u2264\u00b15%<\/td>\u2264\u00b15%<\/td>\u2264\u00b15%<\/td>\u2264\u00b15%<\/td>\n<\/tr>\n
Width of conveyor<\/td>400mm<\/td>600mm<\/td>600mm<\/td>600mm<\/td>\n<\/tr>\n
Out put temperature-Air<\/td>\u226440\u2103<\/td>\u226440\u2103<\/td>\u226440\u2103<\/td>\u226440\u2103<\/td>\n<\/tr>\n
Out put temperature-Water<\/td>\u226425\u2103<\/td>\u226425\u2103<\/td>\u226425\u2103<\/td>\u226425\u2103<\/td>\n<\/tr>\n
Additional Air Cooling-Air<\/td>1500m3\/h<\/td>2000m3\/h<\/td>2000m3\/h<\/td>3000m3\/h<\/td>\n<\/tr>\n
Out put temperature-Water<\/td>200m3\/h<\/td>400m3\/h<\/td>450m3\/h<\/td>500m3\/h<\/td>\n<\/tr>\n
Addition freezing water<\/td>1-2 m3\/h<\/td>2-3m3\/h<\/td>3-4 m3\/h<\/td>3-5m3\/h<\/td>\n<\/tr>\n
Pressure and air balance control precision<\/td>\u00b12pa<\/td>\u00b12pa<\/td>\u00b12pa<\/td>\u00b12pa<\/td>\n<\/tr>\n
Weight\uff08kg\uff09<\/td>2000<\/td>3800<\/td>4800<\/td>5000<\/td>\n<\/tr>\n
Dimension\uff08mm\uff09<\/td>2275x1645x1965<\/td>3400x1620x2200<\/td>4060x1620x2217<\/td>5000x1620x2070<\/td>\n<\/tr>\n
Noise<\/td>\u226460dB<\/td>\u226465dB<\/td>\u226465dB<\/td>\u226465dB<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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GLASS VIALS DEPYROGENATION TUNNEL<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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CASE STUDY<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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1.\u00a0 Pre-heating Warms containers and evaporates residual wash water before they enter the hot zone.<\/p>

2. Hot zone delivers the depyrogenation effect. Reported operating range 220 to 350\u00b0C<\/p>

3. Cooling Returns containers to a fillabletemperature underGrade A air.\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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Let's Work Together<\/h2>\t\t\t\t<\/div>\n\t\t\t\t
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Welcome to get in touch with us. You may fill out the inquiry form on the right side, or reach our team directly via the contact details listed below:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t

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