Automatic Pharmaceutical Small Plastic Bottle Unscrambler Machine for Eye Drops, Nasal Drops & Ear Drops
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Specifications
Description
The Multi Function 30ML Eye / Ear Dropper Bottle Filling Plugging Capping Inspection Machine is an automatic pharmaceutical liquid filling solution for 30ml eye drop, ear drop, nasal drop, and other small-volume dropper bottles. The machine integrates bottle positioning, peristaltic pump filling, inner plug insertion, servo capping, and online inspection in one compact system. With automatic plug and cap detection, no-bottle-no-fill control, and automatic rejection of defective bottles, it helps improve filling accuracy, production efficiency, and packaging consistency. The machine can reach up to 3,600 bottles/hour and can be customized according to bottle, closure, liquid, and production requirements. Automatic 5ml, 10ml, 15ml, 20ml, and 30ml Small Plastic Bottle Unscrambler Machine is specially designed to automatically sort, orient, and feed small plastic bottles for pharmaceutical liquid production lines. It is widely used for manufacturing eye drops, nasal drops, ear drops, ophthalmic solutions, saline products, and other liquid pharmaceutical formulations.
By automatically arranging randomly loaded bottles into an upright position, the machine delivers a continuous, stable bottle supply to downstream filling and capping equipment. It significantly reduces manual handling, improves production efficiency, and supports fully automated pharmaceutical manufacturing.
Designed according to GMP standards, the bottle unscrambler is an ideal front-end solution for modern pharmaceutical packaging lines.

Applications
The automatic bottle unscrambler is suitable for a variety of pharmaceutical and healthcare products, including:
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Eye drops
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Artificial tears
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Preservative-free ophthalmic solutions
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Antibiotic eye drops
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Nasal drops
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Saline nasal sprays
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Ear drops
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Veterinary ophthalmic medicines
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Diagnostic reagents
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Oral liquid products in small plastic bottles
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Cosmetic serums and skincare liquids
Compatible Bottle Sizes

The machine is designed to handle a wide range of small plastic bottles, including:
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5 ml
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10 ml
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15 ml
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20 ml
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30 ml
Supported bottle materials include:
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LDPE bottles
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HDPE bottles
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Plastic squeeze bottles
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Round bottles
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Oval bottles
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Customized plastic bottle designs
Quick-change format parts allow rapid switching between different bottle sizes, making the machine suitable for multi-product manufacturing.
Working Principle
Operators simply load empty bottles into the large-capacity hopper. The unscrambler automatically performs the following operations:

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Random bottle feeding
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Bottle orientation
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Automatic bottle sorting
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Upright bottle positioning
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Continuous bottle discharge
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Stable transfer to the filling and capping machine
The entire process is fully automatic, ensuring a smooth and uninterrupted bottle supply without manual bottle arrangement.
Key Features
High-Speed Bottle Unscrambling
The machine efficiently orients and feeds bottles at high speed while maintaining stable bottle flow.
Benefits include:
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Continuous automatic bottle feeding
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High production efficiency
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Stable bottle orientation
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Reduced manual labor
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Reliable operation during long production runs
It can be seamlessly matched with high-speed pharmaceutical filling lines.
Gentle Bottle Handling
Specially designed bottle handling mechanisms protect lightweight plastic bottles from deformation and scratches.
The machine ensures:
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Smooth bottle transportation
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Low vibration
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Minimal bottle damage
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Stable bottle positioning
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Reliable bottle transfer
This is especially important for soft LDPE eye drop bottles.
Intelligent Automatic Control

The bottle unscrambler is equipped with an advanced automation system featuring:
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Siemens PLC
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Siemens HMI touchscreen
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Servo motor drive
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Frequency-controlled speed adjustment
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Automatic synchronization with downstream equipment
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Fault alarm and diagnostic system
Operators can easily adjust machine parameters through the user-friendly touchscreen interface.
Automatic Bottle Detection
To ensure stable production, the machine includes intelligent monitoring functions such as:
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Bottle shortage alarm
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Bottle jam detection
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Automatic stop when downstream equipment is full
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Automatic restart after production resumes
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Emergency stop protection
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Overload protection
These functions improve equipment reliability while protecting both bottles and machinery.
GMP-Compliant Hygienic Design
The machine is manufactured according to pharmaceutical GMP requirements.
주요 기능은 다음과 같습니다:
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SUS304 stainless steel construction
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Smooth surface finish
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Easy cleaning and maintenance
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Open-frame structure for convenient inspection
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Compact footprint
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Low particle generation
Its hygienic design makes it suitable for pharmaceutical cleanroom environments.
Optional Features

To meet different production requirements, the machine can be configured with:
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Automatic bottle elevator
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Bottle air cleaning system
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Ionized air cleaning
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Dust collection system
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Vision inspection system
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Empty bottle inspection
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Laminar Air Flow (LAF) integration
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Production data recording
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Remote diagnostics
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Customized bottle change parts
Advantages
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Designed specifically for pharmaceutical small plastic bottles
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Suitable for multiple bottle sizes from 5 ml to 30 ml
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High-speed and continuous bottle feeding
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Gentle bottle handling with minimal deformation
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Quick bottle size changeover
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Siemens intelligent control system
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Stable synchronization with filling machines
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GMP-compliant hygienic design
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Easy operation and maintenance
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Long service life with low maintenance costs
Complete Pharmaceutical Production Line Integration
The automatic bottle unscrambler can be integrated into a complete pharmaceutical liquid packaging line, including:
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Automatic Bottle Unscrambler
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Bottle Air Cleaning Machine (optional)
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Eye Drop Filling and Capping Machine
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Labeling Machine
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Cartoning Machine
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Case Packing Machine
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Automatic Palletizer
This integrated solution provides fully automated production from empty bottles to finished packaged products.
Why Choose Our Bottle Unscrambler?
With years of experience in pharmaceutical packaging machinery, we design bottle unscramblers that combine reliability, efficiency, and GMP compliance. Every machine is engineered to provide stable bottle orientation while minimizing downtime and maintenance.
Our services include:
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Customized machine design
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공장 인도 전 검사(FAT)
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현장 인수 테스트(SAT)
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Installation and commissioning
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IQ/OQ documentation support
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Operator training
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Global technical support
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Spare parts supply
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Complete pharmaceutical production line solutions
Whether you are producing eye drops, nasal drops, ear drops, or other small-volume liquid pharmaceuticals, our automatic bottle unscrambler provides the ideal bottle feeding solution for high-efficiency production.
Specifications
| Item | Specification |
|---|---|
| Bottle Volume | 5 ml, 10 ml, 15 ml, 20 ml, 30 ml |
| Bottle Material | LDPE, HDPE, Plastic |
| Bottle Type | Round, Oval, Customized |
| Production Speed | Up to 200 bottles/min (depending on bottle size) |
| Control System | Siemens PLC & HMI |
| Drive System | Servo Motor |
| Machine Material | SUS304 Stainless Steel |
| Power Supply | Customized according to customer requirements |
FAQ
Q1: What bottle sizes can the machine handle?
The standard model is designed for 5 ml, 10 ml, 15 ml, 20 ml, and 30 ml plastic bottles. Customized bottle formats are available upon request.
Q2: Can one machine handle different bottle types?
Yes. By replacing the corresponding change parts and selecting the appropriate recipe on the HMI, the machine can accommodate various bottle sizes and shapes.
Q3: Is the bottle unscrambler suitable for sterile pharmaceutical production?
Yes. The machine features a GMP-compliant hygienic design and can be integrated with Laminar Air Flow (LAF), RABS, or isolator systems to meet aseptic production requirements.
Q4: Can the unscrambler be connected to an automatic filling line?
Absolutely. It is designed to synchronize with automatic eye drop, nasal drop, and ear drop filling and capping machines, creating a continuous, fully automated pharmaceutical packaging line.
