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Successful installation of a high-speed sevoflurane filling machine in Europe. Learn how Reliance provides GMP-compliant sevoflurane filling capping solutions for pharmaceutical manufacturers.


Successful Installation of Automatic Sevoflurane Filling Capping Line for Pharmaceutical Production
Shanghai Reliance Machinery recently completed the installation and commissioning of a high-speed sevoflurane filling machine for a pharmaceutical manufacturer in Europe. The project was designed to provide a reliable and GMP-compliant solution for the automatic filling and capping of sevoflurane inhalation anesthetic liquid.
This successful installation demonstrates Reliance’s expertise in designing and manufacturing sevoflurane filling capping machines for global pharmaceutical companies.
Project Background
Sevoflurane is a widely used inhalation anesthetic agent that requires precise filling technology and strict quality control during production. Due to the characteristics of anesthetic liquids, the filling system must provide:
- Высокая точность наполнения
- Excellent sealing performance
- Minimal product loss
- Stable continuous operation
- Compliance with pharmaceutical GMP requirements
The European customer required an automated filling solution capable of improving production efficiency while ensuring product quality and process reliability.
Customized Sevoflurane Filling Capping Machine Solution
Based on the customer’s production requirements, Shanghai Reliance supplied a complete automatic sevoflurane filling and capping machine with integrated functions:
- Bottle feeding system
- High-precision liquid filling
- Automatic cap placement
- Servo-controlled capping
- Filling volume monitoring
- Cap detection and rejection
- PLC control system
The machine is specially designed for pharmaceutical liquid filling applications, including inhalation anesthetics such as sevoflurane and isoflurane.
Key Features of the Sevoflurane Filling Machine
High-Accuracy Filling System
The machine adopts an advanced filling system to ensure stable filling performance for anesthetic liquids.
Features include:
- Precise filling volume control
- Reduced liquid waste
- Consistent product quality
- Suitable for different bottle sizes
GMP-Compliant Design
The equipment is manufactured with pharmaceutical standards in mind:
- Stainless steel 304/316L construction
- Hygienic product contact parts
- Easy cleaning design
- Cleanroom-compatible structure
The system can be integrated into GMP pharmaceutical production environments.
Automatic Capping and Inspection
The Multi Function 30ML Eye / Ear Dropper Bottle Filling Plugging Capping Inspection Machine is an automatic pharmaceutical liquid filling solution for 30ml eye drop, ear drop, nasal drop, and other small-volume dropper bottles. The machine integrates bottle positioning, peristaltic pump filling, inner plug insertion, servo capping, and online inspection in one compact system. With automatic plug and cap detection, no-bottle-no-fill control, and automatic rejection of defective bottles, it helps improve filling accuracy, production efficiency, and packaging consistency. The machine can reach up to 3,600 bottles/hour and can be customized according to bottle, closure, liquid, and production requirements. sevoflurane filling capping machine integrates automatic cap handling and quality inspection functions.
The system can detect and reject:
- Missing caps
- Incorrect caps
- Loose or abnormal sealing conditions
This helps ensure every finished bottle meets pharmaceutical packaging requirements.
Project Results
After installation and commissioning, the sevoflurane filling line achieved:
- Stable automatic production
- Improved filling efficiency
- Reduced manual operation
- Enhanced product consistency
- Reliable pharmaceutical packaging performance
The successful European installation highlights Shanghai Reliance Machinery’s ability to provide customized inhalation anesthetic filling solutions for international pharmaceutical manufacturers.
Reliable Partner for Sevoflurane Filling Solutions
Shanghai Reliance Machinery specializes in the design and manufacture of:
- Sevoflurane Filling Capping Machine
- Isoflurane Filling Machine
- Pharmaceutical Liquid Filling Machine
- Sterile Liquid Filling Line
- GMP Pharmaceutical Packaging Equipment
With professional engineering experience and global project support, Reliance provides complete solutions for pharmaceutical companies requiring accurate, safe, and efficient liquid filling systems.